As global navigation satellite systems (GNSS) have become critical to aviation operations, threats such as spoofing and jamming have grown in frequency, scale, and sophistication — posing serious risks to flight safety and operational continuity. From commercial airliners losing positional integrity near conflict zones to business aircraft receiving false navigation cues in high-risk regions, these disruptions are no longer isolated or theoretical. This panel will examine real-world incidents, assess the implications for global aviation safety, and explore current and emerging mitigation strategies. Experts will discuss technological countermeasures, operational best practices, and the role of collaboration among industry, regulators, and defense communities in building a more resilient navigation infrastructure.